Gastrointestinal immunology and allergy

Immune dysfunction in allergic diseases such as asthma and atrophy seems to be related to differences in the function and composition of the gut micro biome .The gut micro biome constitutes a highly complex ecosystem which includes eukaryotic fungi, viruses, and some Achaea, although bacteria are the most prominent components. Its composition is generally formed during the first 3 years of life ; however, recent work has suggested that its colonization may begin in utero , contrary to the widely held dogma of the foetus as a sterile environment. Despite its early formation, its composition is highly dynamic and dependent on host-associated factors such as age, diet, and environmental conditions with the major phyla being Actinobacteria, Bacteroidetes, Firmicutes, and Proteobacteria. The gut micro biome is not homogeneous throughout the GIT, showing higher diversity in the oral cavity and intestine, and lower diversity in the stomach, mainly because of the acid environment. Symptoms caused by immediate sensitivity in the gastrointestinal tract typically develop within minutes to 2 hours of ingesting the offending food. Symptoms can include lip, tongue and palatal pruritus and swelling, laryngeal oedema, nausea, abdominal cramping, vomiting and diarrhoea. Severe reactions can result in most or all symptoms associated with anaphylaxis.

 

Related:

Allergy and Clinical Immunology Conference | Allergen Conference | Allergic Conference | Anaphylactic shock Conference | Anaphylaxis Conference | Tolerate | Sensitivity | Intolerant Conference | Hypoallergenic Conference | Hypersensitive Conference | Innate Immunity | Immunogenetics Conference | Immunologic Neuropathies | Immunodiagnostics Conference | Immune Tolerance Conference.

Related Societies and Associations: iCAALL - International Collaboration in Asthma, Allergy and Immunology, International Association of Asthmology (INTERASMA), Pan American Health Organization, Severe Asthma Research Program (SARP), United National Educational, Scientific and Cultural Organization (UNESCO), Allergy and Anaphylaxis Australia (A&AA), Allergy/Asthma Information Association (Canada), Asthma and Allergy Foundation of America (AAFA), Fondation contre les Affectìons Respiratoires et pour l' Education à la Santé (F.A.R.E.S.), Food Allergy Research and Education (FARE) (USA), Immune Deficiency Foundation (IDF) (USA), National Institutes of Health (NIH) (USA), Federation of Clinical Immunology Societies (FOCiS), Allergy and Asthma Network - Mothers of Asthmatics, Inc. (AAN-MA) (USA Allergic Rhinitis and Its Impact on Asthma – ARIA, The Global Initiative for Asthma (GINA), Association Argentina de allergic e Immunologic (AAAI).

 

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