10^th World Summit on Immunology & Immunotherapy August 30-31, 2022 London, UK

Sessions/ Tracks

Track 1: Clinical Immunology and Allergy:

Clinical immunology/allergy specialists in Australia and New Zealand diagnose, treat and manage patients with allergy, primary immune deficiencies and other system disorders. If they need trained in Immuno-pathology, they're going to even be fellows of the Royal College of Pathologists of Australasia (FRCPA). Clinical immunology/allergy specialists are specifically trained to diagnose, treat and manage patients with allergy and other immune diseases. They add hospitals and personal practice, as listed on the ASCIA and a referral from a GP (GP) is required. The body’s system involves a posh network of organs, cells and proteins located throughout the body. The system defends against infections from germs (such as bacteria, viruses, fungi, parasites), and other invaders (such as cancer cells), whilst protecting the body’s own cells.

• Allergic diseases
• Autoimmune diseases
• Immune deficiencies
• Immunosuppression

Track 2: Immune Disorders:

Immune system disorders cause abnormally low activity or over activity of the system. Treatment for autoimmune diseases generally focuses on reducing system activity. The blood cells within the body's system help protect against harmful substances. These substances contain antigens. The system produces antibodies against these antigens that enable it to destroy these harmful substances. once you have an auto-immunedisease, your system doesn't distinguish between healthy tissue and potentially harmful antigens. As a result, the body triggers a reaction that destroys normal tissues. The exact explanation for autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the system. this might happen more often in folks that have genes that make them more vulnerable to autoimmune disorders.

• Rheumatoid arthritis
• Lupus
• Inflammatory bowel disease
• Multiple sclerosis
• Guillain
• Chronic inflammatory demyelinating polyneuropathy
• Psoriasis
• Hashimoto's thyroiditis

Track 3: Infection and Allergy:

Allergens cause the assembly of immunoglobulin E (IgE), an antibody that everyone folks have in small amounts. Allergic persons, however, produce IgE in abnormally quantities. Normally, this antibody is vital in protecting us from parasites, but not from other allergens. These chemicals, in turn, cause inflammation and thus the standard allergic symptoms. this is often how the system becomes misguided and primed to cause an allergy when stimulated by an allergen. Hey Fever is that the commonest of the allergic diseases and refers to seasonal nasal symptoms that are thanks to pollens. Year round or perennial rhinitis is usually because of indoor allergens, like dust mites or molds. Symptoms result from the inflammation of the tissues that line the within of the nose (mucus lining or membranes) after allergens are inhaled. Adjacent areas, just like the ears, sinuses, and throat can also be involved.

• Nasal itching (rubbing)
• Itchy ears and throat
• Post nasal drip (throat clearing)
• Shortness of breath
• Chest tightness
• Redness under the lids and of the eye overall

Track 4: Microbiology and Cellular Immunology:

Microbiology is that the study of microscopic organisms, those being unicellular (single cell), multicellular (cell colony), or a cellular (lacking cells). As an application of microbiology, medical microbiology is typically introduced with medical principles of immunology as microbiology and immunology. The system has been divided into a more primitive innate system and, in vertebrates, an acquired or adaptive system. The system has the potential of self and non-self-recognition. An antigen could also be a substance that ignites the immune response. The cells involved in recognizing the antigen are Lymphocytes. Once they recognize, they secrete antibodies. Antibodies are proteins that neutralize the disease-causing microorganisms. Antibodies don’t directly kill pathogens, but instead identify antigens as targets for destruction by other immune cells like phagocytes or NK cells.

• Natural killer cell immunology
• Thymus and lymphocyte immunobiology
• Immunomodulation
• Immunologic surveillance and tumour immunity
• Delayed-type hypersensitivity or cellular immunity

Track 5: Autoimmunity and Inflammation:

Treatment for autoimmune diseases generally focuses on reducing system activity. Inflammation may be a process by which the body's white blood cells and substances they produce protect us from infection with foreign organisms, like bacteria and viruses. However, in some diseases, like arthritis, the body's defense system -- the system -- triggers an inflammatory response when there are not any foreign invaders to repel. In these diseases, called autoimmune diseases, the body's normally protective system causes damage to its own tissues. Inflammations are often classified as either acute or chronic. Prolonged inflammation, mentioned as chronic inflammation, results in a progressive shift within the sort of cells present at things of inflammation, like mononuclear cells. Conversely, there's pathology where microbial invasion doesn't cause the classic inflammatory response – as an example, parasitosis or eosinophilia. Inflammation isn't a synonym for infection. Inflammation on the other hand describes purely the body's immunovascular response, no matter the cause could even be. But thanks to how often the two are correlated, words ending within the suffix -itis (which refers to inflammation) are sometimes informally described as concerning infection.

• Rheumatoid arthritis
• Inflammatory bowel disease
• Multiple sclerosis
• Graves' disease
• Myasthenia gravis
• Vasculitis
• Swollen joint that's sometimes warm to the touch
• Loss of joint function

Track 6: Immunology and Diseases:

Immunodeficiency’s are often caused during a number of the way, including age, obesity, and alcoholism. In developing countries, malnutrition may be a common cause. AIDS is an example of an acquired immunodeficiency. In some cases, immunodeficiency’s are often inherited, as an example, in chronic granulomatous disease where phagocytes don't function properly. The system must be able to tell self from non-self. An antigen is any substance which can spark an immune response. In many cases, an antigen could also be a bacterium, fungus, virus, toxin, or foreign body. But it can also be one of our own cells that's faulty or dead. Initially, a spread of cell types works together to acknowledge the antigen as an invader. As infection and immune reaction are so intricately intertwined, this book is effective reading to anyone interested by infectious diseases in humans. Maybe within the future prions will need to be included as a replacement sort of infective agent whose rise we are just witnessing. (Information on prion pathology remains hotly debated, and data on routes of transmission and system reactions are still scarce.)

• Celiac disease
• Type 1 diabetes
• Rheumatoid arthritis
• Graves' disease
• Chickenpox
• Pneumonia

Track 7: Immunogenetics:

Immunity is that the power of a personal to acknowledge the “self” molecules that structure one’s own body and to differentiate them from such “nonself” molecules as those found in infectious microorganisms and toxins. This process features a prominent genetic component. Knowledge of the genetic and molecular basis of the mammalian system has increased in parallel with the explosive advances made in vegetative cell and genetics. There are two major components of the system, both originating from an equivalent precursor “stem” cell. The bursa component provides B lymphocytes, a category of white blood cells that, when appropriately stimulated, differentiate into plasma cells. These latter cells produce circulating soluble proteins called antibodies or immunoglobulins. Antibodies are produced in response to substances called antigens, most of which are foreign proteins or polysaccharides. An antibody molecule can recognize a selected antigen, combine with it, and initiate its destruction. This so-called humoral immunity is accomplished through a sophisticated series of interactions with other molecules and cells; a number of these interactions are mediated by another group of lymphocytes, the T lymphocytes, which are derived from the thymus.

• Inflammatory Breast Cancer
• Major histocompatibility complex (MHC)
• Major histocompatibility antigens
• T lymphocytes
• B lymphocyte
• Immunoglobulin

Track 8: Cancer Immunology and Immunotherapy:

Cellular immunity depends mainly on the power of DCs to require up and process antigens within the peripheral blood and tissues. In cancer, this process isn't robust enough to supply meaningful antitumor responses. Monoclonal antibodies are proteins produced by B-cells that bind to a selected antigen. they're currently one among the foremost successful sorts of cancer immunotherapy. we should always differentiate between monoclonal antibody-based cancer therapy and monoclonal antibody-based immunotherapy of cancer. this will be illustrated by the differences in their mechanisms of action. Anti-neoplastic agents like bevacizumab block ligand–receptor interaction, thereby affecting growth or survival pathways, where monoclonal antibodies like rituximab cause antibody-dependent cellular cytotoxicity and complement-mediated cytotoxicity. Antibodies also are getting used to reinforce the strength of the immune reaction. As mentioned earlier, activated T-cells and tumour cells express CTLA4 receptors as an immune-suppressive mechanism to guard against autoimmunity and to flee elimination. Antagonism of those receptors has shown antitumor benefit. for instance, ipilimumab inhibits the receptor CTLA4, permitting persistent T-cell activation. Similarly, PD1 is expressed on activated T- and B-cells and when sure to by PD1 ligand they become deactivated (10-12). Tumour cells tend to overexpress PD1 ligands, allowing them to deactivate this response.

• Cell-based immunotherapy of cancer
• Antibody-based immunotherapy of cancer
• Cytokine-based immunotherapy of cancer
• Anti CTLA4
• Anti-PD1
• Hodgkin's lymphoma

Track 9: Neonatal and Pediatric Immunology:

Neonatology could also be a subspecialty of pediatrics that consists of the medical care of newborn infants, especially the ill or premature newborn. It is a hospital-based specialty, and is typically practiced in neonatal medical care units (NICUs). Neonatal Nurse Practitioners (NNPs) are advanced practice nurses that concentrate on neonatal care. They are considered providers and sometimes share the workload of NICU care with resident physicians. They are ready to treat, plan, prescribe, diagnose and perform procedures within their scope of practice, defined by governing law and therefore the hospital where they work. A medical doctor who focuses on this area is understood as a pediatrician, or paediatrician. Pediatric physiology directly impacts the pharmacokinetic properties of medicine that enter the body. The absorption, distribution, metabolism, and elimination of medicines differ between developing children and grown adults. Despite completed studies and reviews, continual research is required to raised understand how these factors should affect the choices of healthcare providers when prescribing and administering medications to the pediatric population.

• Absorption
• Distribution
• Metabolism
• Elimination
• Neonatal cancer
• Neonatal conjunctivitis
• Neonatal lupus erythematous

Track 10: Veterinary Allergology:

Allergic diseases are frequently observed in veterinary practice. With increasing standards in veterinary care, intradermal testing and allergen immunotherapy were introduced to small animal practice within the mid‐nineteen hundred; later, serum testing for allergen‐specific IgE was developed for dogs, cats and horses. Although atopic asthma is rare within the dog and not much is known with regard to rhinitis, atopic eczema may be a frequently encountered disease in small animal practice and attention of research in veterinary dermatology. Horses develop skin and respiratory disorders that are attributed to allergy. While recurrent airway obstruction, previously called ‘heaves’, has many similarities to human asthma, the simplest understood allergic disease in horses is insect‐bite hypersensitivity. an efficient treatment for this disease still remains elusive. The dog, cat and horse, although data on the main allergens relevant for dogs, cats and horses are limited. In contrast to environmental allergens, studies evaluating food allergens in medicine are rare. Food rechallenges after elimination diets are notoriously difficult and not performed during a double‐blinded fashion.

• Zoonotic bacteria
• Allergic Reactions to venom
• Parasite vaccines
• Veterinary viral vaccines
• Inhalant allergy

Track 11: Asthma and COPD:

Asthma could also be a chronic inflammatory disorder of the airways. The chronic inflammation is said to airway hyper responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness and coughing, particularly in the dark or in early morning. These episodes are usually associated with widespread, but variable, airflow obstruction within lung that's often reversible either spontaneously or with the treatment. Asthma could also be a significant global unhealthiness with an estimated 300 million affected individuals. People of all ages are suffering from this illness that, when uncontrolled, can place severe limits on lifestyle and is usually fatal. Clinical manifestations of asthma are often controlled with appropriate treatment. COPD is one among the main causes of chronic morbidity and mortality worldwide. many of us suffer from this disease for years and die prematurely from its complications. COPD is that the fourth leading explanation for death within the planet, and further increases in its prevalence and mortality are often predicted within the approaching decades. COPD may be a pulmonary disease with some significant extra pulmonary effects which will contribute to the severity in individual patient. Its pulmonary component is characterized by airflow limitation that's not fully reversible. Cigarette smoking is that the most ordinarily encountered risk factor for COPD, although in many countries, pollution resulting from the burning of wood and other biomasses fuels has also been identified as a COPD risk factor.

• Airway inflammation
• Eosinophils
• T lymphocytes
• Chemokines
• Neutrophils
• Lipid mediators
• Pro inflammatory cytokines

Track 12: Food Allergies and Infections:

An allergy is an abnormal immune response to food. The symptoms of the allergy may range from mild to severe. they'll include itchiness, swelling of the tongue, vomiting, diarrhoea, hives, trouble breathing, or low sign. This typically occurs within minutes to several hours of exposure. When the symptoms are severe, it's mentioned as anaphylaxis. A food intolerance and gastrointestinal disorder are separate conditions, undue to an immune reaction. The common allergies vary counting on the country. Risk factors include a case history of allergies, vitamin D deficiency, obesity, and high levels of cleanliness. Allergies occur when immunoglobulin E (IgE), a neighborhood of the body's system, binds to food molecules. A protein within the food is usually the matter. This triggers the discharge of inflammatory chemicals like histamine. Diagnosis is usually supported a medical history, elimination diet, skin prick test, blood tests for food-specific IgE antibodies, or oral food challenge. allergy is an abnormal response to a food triggered by your body's system. In adults, the foods that the bulk often trigger allergies include fish, shellfish, peanuts, and tree nuts, like walnuts. Problem foods for kids can include eggs, milk, peanuts, tree nuts, soy, and wheat. The allergy could also be mild. In rare cases it can cause a severe reaction called anaphylaxis.

• Itching or swelling in your mouth
• Vomiting, diarrhoea, or abdominal cramps and pain
• Hives or eczema
• Tightening of the throat and trouble breathing
• Drop in blood pressure

Track 13: Vaccines and Immunization:

Vaccines are wont to boost your system and stop serious, life-threatening diseases. Vaccines help protect against many diseases that want to be far more common. Many of these infections can cause serious or life-threatening illnesses and will cause life-long health problems. due to vaccines, many of these illnesses are now rare. this is often a natural thanks to affect infectious diseases. Live virus vaccines use the weakened (attenuated) sort of the virus. The measles, mumps, and rubella (MMR) vaccine and thus the varicella (chickenpox) vaccine are examples. Killed (inactivated) vaccines are made from a protein or other small pieces taken from a plague or bacteria. The pertussis (pertussis) vaccine is an example. Toxoid vaccines contain a toxin or chemical made by the bacteria or virus. they create you immune to the harmful effects of the infection, instead of to the infection itself. Examples are the diphtheria and tetanus vaccines. Biosynthetic vaccines contain manmade substances that are very almost like pieces of the virus or bacteria. The hepatitis B vaccine is an example.

• Chickenpox vaccine
• DTaP immunization (vaccine)
• Hepatitis A vaccine
• Hepatitis B vaccine
• HPV vaccine
• Influenza vaccine
• Meningococcal vaccine

Track 14: Diagnostic Immunology:

Immunology is that the study of molecules, cells, and organs that structure the system. The function of the system is to acknowledge self-antigens from non-self-antigens and defend the body against non-self (foreign) agents. Through specific and non-specific defence mechanisms, the body’s system is during a position to react to microbial pathogens and protect against disease. If the inflammation remains aggravated, antibody-mediated immune reaction is activated and differing kinds of immune cells are engaged to resolve the disease. The system consists of cellular and humoral elements. to assist within the diagnosis of disease caused by infectious microorganisms, immunoassays are developed. Serum is then isolated and thus the concentration of antibodies is measured through various methods. Most assays believe the formation of giant immune complexes when an antibody binds to a specific antigen which can be detected in solution or in gels. Recent methods employ pure antibodies or antigens that are immobilized on a platform which are often measured using an indicator molecule. These methods provide high sensitivity and specificity and have become standard techniques in diagnostic immunology.

• Immunoglobulin-G
• Immunoglobulin-M
• Serology
• Precipitin
• Erythrocytes
• Agglutination

Track 15: Gastrointestinal immunology and allergy:

Immune dysfunction in allergic diseases like asthma and atrophy seems to be associated with differences within the function and composition of the gut micro biome. The gut micro biome constitutes a highly complex ecosystem which incorporates eukaryotic fungi, viruses, and a few Achaea, although bacteria are the foremost prominent components. Its composition is usually formed during the primary 3 years of life; however, recent work has suggested that its colonization may begin in utero , contrary to the widely held dogma of the foetus as a sterile environment. Despite its early formation, its composition is very dynamic and hooked in to host-associated factors like age, diet, and environmental conditions with the main phyla being Actinobacteria, Bacteroidetes, Firmicutes, and Proteobacteria. The gut micro biome isn't homogeneous throughout the GIT, showing higher diversity within the mouth and intestine, and lower diversity within the stomach, mainly due to the acid environment. Symptoms caused by immediate sensitivity within the alimentary canal typically develop within minutes to 2 hours of ingesting the offending food. Symptoms can include lip, tongue and palatal pruritus and swelling, laryngeal oedema, nausea, abdominal cramping, vomiting and diarrhoea. Severe reactions may result in most or all symptoms related to anaphylaxis.

• Cross-contamination
• Facial angioedema
• Tingling of the lips, tongue, palate and throat.
• Oropharyngeal itching
• Anaphylaxis

Track 16: Cancer and Tumour Immunology:

However, the system could even be able to mount an attack against the few tumour cells that are spared by the chemotherapeutic agent. there's an increased incidence of malignancies in immuno-deficient patients like AIDS patients who are susceptible to Kaposi sarcoma and transplant patients who are susceptible to Epstein Barr virus (EBV)-induced lymphoma. Tumor-specific antibodies and T lymphocytes. Hosts are often specifically immunized against various sorts of tumors demonstrating tumour antigens can elicit an immune reaction . A tumour that grows in an animal strain also will grow in another animal belonging to the same inbred strain obtained by repeated brother-sister mating’s. These animals express the same MHC molecule and are mentioned as syngeneic. However, most conventional animal populations are allogeneic and have various MHC haplotypes. Thus, a tumour transferred from one animal to a special animal belonging to an outbred strain is rejected thanks to the allo-MHC rather than the TSTA. A tumour transferred from an animal belonging to a minimum of one species a special">to a special animal belonging to a special species is rapidly rejected because the animals are xenogeneic.

• Papova (papilloma, polyoma) viruses
• Human T-lymphotropic viruses
• Tumour-specific transplantation antigens
• Tumour associated transplantation antigens
• Bacillus Calmette-Guerin
• Hepatitis B vaccine

Track 17: Parasite Immunology:

Parasite Immunology may be a world journal dedicated to research on all aspects of parasite immunology in human and animal hosts. Emphasis has been placed on how hosts control parasites, and thus the immunopathological reactions which happen within the course of parasitic infections. Extensive research shows that parasitic worms have the facility to deactivate certain system cells, leading to a gentler immune response. Often, such a response is beneficial to both parasite and host, according to Professor of Medical Microbiology Graham Rook of University College London. This immune "relaxation" is incorporated throughout the system, decreasing immune responses against harmless allergens, gut flora, and thus the body itself. In their Parasite Immunology article on worms and viral infections, Dr. Kamal et al. explain why some parasitic worms aggravate the immune response. Because parasitic worms often induce Th2 cells and cause suppressed Th1 cells, problems arise when Th1 cells are needed. within the past, helminthic were thought to easily suppress T-helper Type 1 (Th1) cells while inducing T-helper Type 2 (Th2) cells. However, helminthic also regulate Th2-caused diseases, like allergy and asthma.

• Bacteriology
• Fungal infection
• Helminthic disease
• Parasites
• Parasitology
• Protozoan disease

Track 18: Immune Tolerance:

Immune tolerances are often defined as a state during which a T -cell cannot answer antigen. The T cell "tolerates" the antigen. A state of unresponsiveness to a specific antigen or group of antigens to which a private is usually responsive. Immune tolerance is achieved under conditions that suppress the immune response and is not just the absence of an immune reaction. it's the prevention of an immune reaction against a specific antigen. as an example, the system is usually tolerant of self-antigens, so it doesn't usually attack the body's own cells, tissues, and organs. However, when tolerance is lost, disorders like autoimmune disease or allergy may occur. Encompasses the range of physiological mechanisms by which the body reduces or eliminates an immune response to particular agents. Typically, a change within the host, not the antigen, is implied. Though some pathogens can evolve to subside virulent in host-pathogen coevolution, tolerance doesn't ask the change within the pathogen, but are often wont to describe the changes in host physiology. Nor does it ask other kinds of non-reactivity like immunological paralysis.

• Central tolerance
• Peripheral tolerance
• Allograft tolerance
• Foetal development
• Fetomaternal tolerance

Target Audience

• Immunologists
• Pathologists
• Pharmacologists
• Scientists
• Young research fellows
• Research Scholars
• Residents, Fellows & Post Docs
• Business Executives & Directors
• Professors
• Students
• CEO
• Organizations
• Associate and Assistant Professors in Immunology
• Association heads and Professors
• Immunology laboratory heads
• CEOs, COOs, Directors, Vice Presidents, Co-directors, Managing Directors,
• Students and other affiliates related to the area of Immunology and Immunotherapy.

Immunotherapy Drugs Market – Forecasts (2022 - 2026): 

Top-down and bottom-up methods were used to estimate and validate the size of the global cancer immunotherapy market and to evaluate the size of various other dependent submarkets. The Immunotherapy Drugs Market was valued at USD 164.68 billion in 2020, and it is predicted to reach USD 276.51 billion by 2026, registering a CAGR of 8.41% during the forecast period. The major factors accrediting to the growth of the immunotherapy drugs market are the rising adoption of targeted therapy over traditional therapy, emergence of biosimilars, rising prevalence of chronic diseases and lifestyle disorders, and rising demand for monoclonal antibodies.

The influence of COVID-19 on the immunotherapy drugs market is constructive because many companies are currently focused on developing immunotherapy-based drugs or vaccines for COVID-19. Currently, BioNTech SE, in collaboration with Pfizer Inc., is conducting a phase III clinical trial to assess the safety, tolerability, and immunogenicity of BNT162b2 against COVID-19 in healthy participants.

The growing prevalence of cancer and increasing investment in R&D activities for the development of cancer cell therapies is also stimulating market growth. The global Cancer Immunotherapy Market size is expected to reach USD 168.48 billion in 2028, registering a CAGR of 10.1% over the forecast period, according to a new report by Reports and Data. Key factors driving cancer immunotherapy market revenue growth are increasing adoption of immunotherapy drugs over conventional treatments, increasing prevalence of cancer, increasing investments for development of biosimilars and monoclonal antibodies, along with a favorable drug approval scenario.

Related Societies and Associations:

• American Academy of Allergy, Asthma and Immunology (AAAAI)
• American Board of Allergy and Immunology (ABAI)
• Association of Allergy Asthma and Immunology "Buenos Aires" (AAIBA)
• Association of Universities and Colleges of Canada (AUCC)
• Canadian Society of Allergy and Clinical Immunology (CSACI)
• Canadian Society for Immunology (CSI)
• Macedonian Society for Basic Clinical Immunology & Allergology (MSBCIA)
• Norwegian Society for Immunology (NSI)
• Australasian Society for Immunology (ASI)
• Association of Medical Laboratory Immunologists (AMLI)
• International Cytokine Society (ICS)
• Society for Leukocyte Biology (SLB)
• Society for Immunology and Immunopathology (SIIP)
• Federation of Clinical Immunology Societies (FOCIS)

Universities Related to Immunology

• Harvard University
• University of California--San Francisco
• Massachusetts Institute of Technology
• Johns Hopkins University
• Rockefeller University
• Yale University
• Washington University in St. Louis
• Stanford University
• University of Oxford
• University of Washington
• University of Pennsylvania
• Karolinska Institute
• University of Melbourne
• Icahn School of Medicine at Mount Sinai
• Cornell University
• Emory University
• University of Zurich
• Imperial College London
• University of California--San Diego
• University of Munich